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Membrane Solutions Syringe Filters provides high quality filters which are well packaged. Syringe filters are overprices for decades due to monopoly. With the developments of membrane manufacturing technology and more manufacturers involved the prices of membrane filters should be going down, but in scientific research fields the prices of membrane filters, especially the syringe filter prices, are remaining way too high. At Green BioResearch we are not only thinking about pollution reduction in research fields but also caring about the bio-consumable prices. We are trying our best to bring down prices of lab research consumables while keep the same or better product qualities. Grand money should be spent on more important things, such as exploring new research fields, etc. We offer fair and competitive prices compared to some famous brands, such as, Whatman syringe filter, Nalgene syringe filter, etc. Prices should be researchers’ first concerns when similar products available.

Now let’s talk about the Syringe Filter itself. How to choose the right syringe filter — syringe filter selection based on materials.

 

 

syringe-filter-membrane-materials

How to Choose Right Syringe Filter — Filter Membrane Materials

How to choose right syringe filter is important for filtration. In this blog we are going to talk about the membrane materials used for manufacturing syringe filters. Please check the filter membrane chemical compatibility for the liquids you are going to filter.

Cellulose Acetate (CA)

Cellulose acetate is a very low protein binding membrane that is ideal for aqueous based samples and biological samples. It is a lower protein binder than either polyethersulphone or PVDF membranes, but has a lower chemical resistance than regenerated cellulose (RC). CA is a strong membrane mechanically and hydrophilic.

Membrane: HPLC Certified Cellulose Acetate
Protein Binding: <24ug/cm2

  • Use with: Aqueous samples
  • Don’t use with: Organic solvents
  • Sterilization: Syringe filters can be sterilized by autoclave at 125° for 15 minutes.
  • Applications: Biological samples, tissue culture media filtration, preparation of aqueous samples for HPLC

Glass Microfiber (GMF)

Glass Microfibre filters should be used as a pre-filter for samples with a high particulate content. GMF membranes are available with a higher pore size than other membranes and is tolerant to most solvents.

  • Membrane: Binder-free Glass Microfiber
  • Use with: Heavily contaminated samples
  • Don’t use with: Benzyl alcohol
  • Sterilization: Syringe filters can be sterilized by autoclave at 125° for 15 minutes.
  • Applications: Dissolution testing, filtration of high particulate samples, air filtration, recovery of DNA from biological samples

NYLON (NY)

Nylon membrane has high strong mechanical strength, chemical stability, can be tolerated by most organic solvents, extremely low in extractables, good thermal stability (up to 50°C), natural hydrophilic and the majority of water solution filter characteristics. It more often applied to the common organic solvent HPLC mobile phase filtering.

  • Membrane: HPLC Certified Nylon.
  • Use with: Bases, Most HPLC solvents, Alcohols, Aromatic Hydrocarbons, THF.
  • Don’t use with: Acids, Aggressive Halogenated hydrocarbons, protein samples (Nylon is a high binder)
  • Sterilization: Syringe filters can be sterilized by autoclave at 125° for 15 minutes.
  • Applications: General Laboratory filtration, most HPLC samples

Polyethersulphone (PES)

Polyethersulphone is a hydrophilic membrane that has very low protein binding and high flow characteristics. It is also certified for ion chromatography. Polyethersulphone is more heat resistant than most membranes, and can be used to 100°C.

  • Membrane: ICP Certified PES (Polyethersulfone)
  • Use with: Strong bases, alcohols, proteins, peptides
  • Don’t use with: acids, ketones, esters, halogenated or aromatic hydrocarbons.
  • Sterilization: Syringe filters can be sterilized by autoclave at 125° for 15 minutes.
  • Applications: Ion chromatography, tissue culture filtration, filtration of proteins and nucleic acids, high-temperature liquids.

Polypropylene (PP)

Hydrophilic polypropylene membranes are chemically resistant and suitable for a wide variety of organic and aqueous based samples. They are low protein binders and can be used with strong acids and bases without prewetting.

  • Membrane: Hydrophilic Polypropylene
  • Use with: Acids/Bases, general HPLC analysis
  • Limited resistance with: MeCl and Chloroform.
  • Sterilization: Syringe filters can be sterilized by autoclave at 125° for 15 minutes.
  • Applications: Filtration of biological samples, aggressive organic solvents.

Polytetrafluoroethylene (PTFE)

PTFE membranes are chemically resistant to nearly all solvents, acids and bases. The membrane has low extractable and good thermal stability. PTFE is hydrophobic and requires pre-wetting prior to use with aqueous solvents.

  • Membrane: HPLC certified PTFE, with polypropylene support
  • Use with: Aggressive solvents, strong acids, alcohols, bases, aromatics
  • Don’t use with: Aqueous samples without prewetting (causes high backpressure)
  • Sterilization: Syringe filters can be sterilized by autoclave at 125° for 15 minutes.
  • Applications: Filtration of aggressive organic or highly basic solutions, transducer protectors.

Polyvinylidene Difluoride (PVDF)

Polyvinylidene difluoride is a hydrophilic membrane that is suitable for most general biological sample filtration. It has a broad chemical compatibility and is a low protein binder and so a good choice where high protein recovery is required.

  • Membrane: HPLC-certified PVDF
  • Use with: Alcohols, weak acids, proteins, peptides and other biomolecules
  • Don’t use with: Some strong acids, bases, esters, ethers or ketones.
  • Sterilization: Syringe filters can be sterilized by autoclave at 125° for 15 minutes.
  • Applications: General biological filtration, filtration of samples for high protein recovery.

Regenerated Cellulose (RC)

Regenerated cellulose is a hydrophilic solvent resistant membrane. It is a very low protein binder and is ideal for low nonspecific binding applications; tissue culture media filtration and general biological sample filtration

  • Membrane: HPLC Certified Regenerated Cellulose
  • Use with: Proteins, Peptides and other biomolecules
  • Don’t use with: Strong acids, Chloroform, THF.
  • Sterilization: Syringe filters can be sterilized by autoclave at 125° for 15 minutes.
  • Applications: Low nonspecific binding applications, Tissue culture media filtration and general biological sample filtration

 

 

 

Syringe Filter Materials

Out Diameter (mm)

Filter Pore Size (uM)

Nylon Syringe Filter

4, 13, 17, 25, 30

0.1, 0.22, 0.45, 1.0, 3.0, 5.0

PTFE Syringe Filter

4, 13, 17, 25, 30

0.22, 0.45, 1.0, 3.0, 5.0

Hydrophilic PTFE Syringe Filter

4, 13, 17, 25, 30

0.22, 0.45

PVDF Syringe Filter

4, 13, 17, 25, 30

0.22, 0.45

PES Syringe Filter

4, 13, 17, 25, 30

0.1, 0.22, 0.45

CA Syringe Filter

4, 13, 17, 25, 30

0.22, 0.45, 3.0

Glass Fiber Syringe Filter

4, 13, 17, 25, 30

0.7, 1.0

MCE Syringe Filter

4, 13, 17, 25, 30

0.22, 0.45, 3.0

G-MP Syringe Filter

25

0.2, 0.45

Sterile Syringe Filter

4, 13, 25, 30

0.1, 0.22, 0.45

50mm Venting Filter

50

0.1, 0.22, 0.45

Reusable Syringe Filter

13, 25

 

 

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